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Maintain your brain

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Dementia Australia resources

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Papers / research


National Academies of Sciences, Engineering, and Medicine (2017) Preventing cognitive decline and dementia: A way forward. Washington, DC: The National Academies Press. doi: https://doi.org/10.17226/24782.
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The National Institute on Aging (NIA) initiated this study with the National Academies of Sciences, Engineering, and Medicine to take stock of the current state of knowledge on interventions for preventing cognitive decline and dementia, to help shape the messages NIA conveys to the broader public about these conditions, and to inform future actions and research in this area. 


Anstey, K. J., Eramudugolla, R., Hosking, D. E., Lautenschlager, N. T., & Dixon, R. A. (2015). Bridging the Translation Gap: From Dementia Risk Assessment to Advice on Risk Reduction. The journal of prevention of Alzheimer's disease2(3), 189–198. https://doi.org/10.14283/jpad.2015.75 
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This narrative review provides capsule summaries of current evidence for 25 risk and protective factors associated with AD and dementia according to domains including biomarkers, demographic, lifestyle, medical, and environment. We identify the factors for which evidence is strong and thereby especially useful for risk assessment with the goal of personalising recommendations for risk reduction.


Prince, M.,  Albanese, E.,  Guerchet, M.,  Prina, M.  (2014) World Alzheimer Report 2014: Dementia and Risk Reduction. An Analysis of Protective and Modifiable Factors
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This report critically examines the evidence for the existence of modifiable risk factors for dementia. It focuses upon sets of potential modifiable risk factors in four key domains; developmental, psychological and psychosocial, lifestyle and cardiovascular risk factors.

Brain training

 

  • Brain training involves repetitive cognitive exercises that gradually increase in difficulty as performance improves
  • Brain training can be effective at improving specific cognitive functions in healthy people without dementia, but it is unclear how long the benefits may persist
  • Currently, there is limited evidence implicating brain training in lowering risk of dementia
  • In older people, brain training may increase the ability of the hippocampus (memory) and the frontal lobe (planning and problem solving) to communicate with one another.  This increased connectivity partly explains the cognitive benefits of brain training.

Dr Amit Lampit & Dr Alex Bahar-Fuchs  (2020) Training your brain in lockdown.  Pursuit 19 April 2020

The profound changes in our lifestyle due to COVID-19 social distancing may require us to take more deliberate actions to exercise our thinking skills. This article provides some tips.
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Shah, T. M., Weinborn, M., Verdile, G., Sohrabi, H. R., & Martins, R. N. (2017). Enhancing Cognitive Functioning in Healthly Older Adults: a Systematic Review of the Clinical Significance of Commercially Available Computerized Cognitive Training in Preventing Cognitive Decline. Neuropsychology review27(1), 62–80. https://doi.org/10.1007/


Burch D. (2014). What could computerized brain training learn from evidence-based medicine?. PLoS medicine11(11), e1001758. https://doi.org/10.1371/journal.pmed.1001758


Lampit, Amit, Valenzuela, Michael & Gates, Nicola J. (2015). Computerized cognitive training is beneficial for older adults. Journal of the American Geriatrics Society63(12), 2610-2612.  DOI: 10.1111/jgs.13825

Websites

Cogtale: Cognitive Treatments Article Library and Evaluation

CogTale is a comprehensive database of design (methodological) features and summary results from all relevant trials of cognitive interventions in the field of cognitive ageing.

The scientists behind CogTale are passionate about research on cognitive interventions in older age, and about assisting consumers in making informed treatment decisions, by providing up-to-date, evidence-based information on cognitive intervention treatments. 


ANU Alzheimer's Disease Risk Index (ANU-ADRI)

The ANU-ADRI is an evidence-based, validated, tool aimed at assessing individual exposure to risk factors known to be associated with an increased risk of developing Alzheimer's disease in late-life, that is, over the age of 60 years.

The ANU-ADRI is intended to provide a systematic individualised assessment and report on Alzheimer's disease risk factor exposure. It may be useful for individuals who wish to know their risk profile and areas where they can reduce their risk. It may also be useful to clinicians who would like their patients to record their current risk profile for discussion at their next medical appointment. The ANU-ADRI is also used in research projects that aim to evaluate methods of reducing risk of Alzheimer’s disease.